NO.

Product Name

Structure

Status

101

Carbamazepine intermediates 卡马西平中央体

101-1

Iminodibenzyl   

亚氨基二苄 （IDB）

CAS: 494-19-9

Commercial

101-2

Iminostilbene Carbonyl Chloride

亚氨基芪甲酰氯 (ISBCC)

CAS:33948-22-0

Commercial

102

Carbamazepine Bromine Free intermediates 无溴卡马西平中央体

102-1

Iminostilbene

亚氨基芪 (ISB)

CAS:256-96-2

Commercial

103

Oxcarbazepine intermediates 奥卡西平中央体

103-1

10-Methoxy Iminostilbene

10-甲氧基亚氨基芪 (10-MISB)

CAS:4698-11-7

Commercial

104

Paroxetine intermediates 帕罗西汀中央体

104-1

(3S,4R)-3-(3,4-Methylene-dioxyphenoxy-methyl)-4-

(4’-fluorophenyl)-N-methylpiperidine

N-甲基帕罗西汀

CAS:110429-36-2

Commercial

105

Venlafaxine intermediates 文拉法辛中央体

105-1

1-(4-Methoxyphenyl)-2-Aminoethyl Cyclohexanol Hydrochloride

1-(4-甲氧基苯基)-2-胺基乙基环己醇盐酸盐

CAS:130198-05-9

Commercial

201

Ketoprofen intermediates 酮基布洛芬中央体

201-1

2-(3-Benzoylphenyl)Propionitrile

间丙腈基二苯酮

CAS:42872-30-0

Commercial

NO.

Product Name

Structure

Status

301

Gliclazide intermediates 格列齐特中央体

301-1

N-Amino-Aza-3-Bicyclo[3,3,0]Octane Hydrochloride

N-氨基-氮杂-3-二环[3,3,0]辛烷盐酸盐

CAS:58108-05-7

Commercial

401

Cabapenem intermediates 培南中央体

401-1

(3R,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)

ethyl]azetidin-2-one

AOSA (4-AA)  4-乙酰氧基氮杂环丁酮

CAS: 76855-69-1

Commercial

401-2

Thienamycin p-nitrobenzyl ester hydrochloride (N-methylpyrrolidinone solvate)

硫霉素对硝基苯甲酯盐酸盐(N-甲基吡咯烷酮溶剂化合物)

CAS：442847-66-7

Commercial

402

Meropenem intermediates 美罗培南中央体

402-1

P-nitrobenzyl(1r,5r,6s)-6-[(1r)-1-hydroxyethyl]-2-[(diphenylphosphono)oxy]-1-methylcarbapen-2-em-3-carboxylate

MAP  [4R-[4a,5b,6b(R*)]]-3-二苯基磷酰氧基-6-(1-羟基乙基)-4-甲基-7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸对硝基苄酯
1b-甲基碳青霉烯双环母核（杂氮双环磷酸酯）

CAS: 90776-59-3

Commercial

402-2

(R)-4-Nitrobenzyl-2-diazo-4-((2R,3S)-3-((R)-1-hydroxyethyl)-4-oxoazetidin-2-yl)-3-oxopentanoate

 (3S,4R)-4-[(1R)-1-羟乙基]-3-[(1R)-1-甲基-3-沉氮-3-对硝基苄基氧羰基-2-氧代（美罗中央体F9）

CAS:137391-68-5

Commercial

402-3

(2S,4S)-2-[(Dimethylamino)carbonyl]-4-mercapto-1-Pyrrolidinecarboxylic acid-(4’-nitrophenyl)methyl ester

(2S,4S)-2-[(二甲氨基)甲酰-4-巯基-1-吡咯烷甲酸(4’-硝基)苄酯

CAS: 96034-64-9

Commercial

NO.

Product Name

Structure

Status

501

Sitagliptin intermediates 西他列汀中央体

501-1

Boc-(R)-3-Amino-4-(2.4.5-trifluoromethyl) butyrate

Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸

CAS: 486460-00-8

Commercial

501-2

2,4,5-Trifluorophenylacetic acid

2,4,5-三氟苯乙酸

CAS: 209995-38-0

Commercial

501-3

3-trifluoro methyl-[1,2,4]triazole[4,3-a]piperazine hydrochloride

3-(三氟甲基)-5,6,7,8-四氢-[1,2,4]三唑并[4,3-a]吡嗪盐酸盐

CAS: 762240-92-6

Commercial

501-4

(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

Sitagliptin Base

(3R)-3-氨基-1-[3-(三氟甲基)-5,6,7,8-四氢-1,2,4-三唑并[4,3-a]吡嗪-7-基]-4-(2,4,5-三氟苯基)丁-1-酮

西他列汀单体

CAS: 486460-32-6

Commercial

501-5

4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

(2Z)-4-氧代-4-[3-(三氟甲基)-5,6-二氢-[1,2,4]三唑并[4,3-a]吡嗪-7-(8H)-基]-1-(2,4,5-三氟苯基)丁-2-酮

CAS: 764667-65-4

Commercial

601

Sulfasalazine intermediates 柳氮磺吡啶中央体

601-1

Sulfapyridine

磺胺吡啶

CAS: 144-83-2

Commercial

701

Imatinib intermediates 伊马替尼中央体

701-1

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride

4-[(4-甲基哌嗪-1-基)甲基]苯甲酸二盐酸盐

CAS:106261-49-8

Commercial

701-2

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine N-(5-氨基-2-甲基苯基)-4-(3-吡啶基)-2-氨基嘧啶

CAS:152460-10-1

Commercial

NO.

Product Name

Structure

Status

801

Relebactam intermediates 瑞莱巴坦中央体

801-1

(2S,5S)-5-hydroxypiperidine-2-carboxylic acid

(2S,5S)-5-羟基哌啶-2-羧酸

CAS:63088-78-8

Commercial

801-2

tert-butyl 4-((1R,2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]

octane-2-carboxamido) piperidine-1-carboxylate

4-[[[(1R,2S,5R)-6-羟基-7-氧代-1,6-二氮杂双环[3.2.1]辛烷-2-基]羰基]氨基]-1-哌啶羧酸叔丁酯

CAS:1174020-64-4

Commercial

901

Avibactam intermediates 阿维巴坦中央体

901-1

(2S,5R)-5-((4-methoxybenzyl)oxy)amino)piperidine-2-carboxamide

Commercial

901-2

(2S,5R)-6-((4-methoxybenzyl)oxy)-7-oxo-1,6-diazabicyclo

[3.2.1]octane-2-carboxamide

Commercial

901-3

tetrabutylammonium (2S,5R)-2-carbamoyl-

7-oxo-1,6-diazabicyclo [3.2.1]octan-6-yl sulfate

(1R,2S,5R)-2-(氨基羰基)-7-氧代-1,6-二氮杂双环[3.2.1]辛-6-基硫酸酯(四丁基铵)盐

CAS: 1192651-80-1

Commercial

1001

 Cilastatin intermediates 西司他丁中央体

1001-1

(S,Z)-7-chloro-2-(1,2,2-trimethylcyclopropane-1-

carboxamido)hept-2-enoic acid

7-氯-2-[[[(1S)-2,2-二甲基环丙基]羰基]氨基]-2-庚烯酸

CAS：877674-77-6

Commercial

NO.

Product Name

Structure

Status

1101

Semaglutide intermediates 司美格鲁肽中央体

1101-1

Fmoc-Glu(OtBu)-Gly-OH （FMC）

(S)-2-(2-((((9H-芴-9-基)甲氧基)羰基)氨基)-5-(叔丁氧基)-5-氧代戊酰胺基)乙酸

司美格鲁肽中央体  (TTA-A20)

CAS:866044-63-5

Commercial

1101-2

Fmoc-Lys(AEEA-AEEA-g-Glu(OtBu)-Oct(OtBu))-OH

司美格鲁肽中央体  (MAT)

 CAS:1662688-20-1

Commercial

1101-3

Fmoc-Gly-Arg(Pbf)-OH  

司美格鲁肽中央体 (FMC)

CAS:L1048377-78-1

Commercial

1101-4

Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH  

司美格鲁肽中央体 (TTA)

CAS:1890228-73-5

Commercial

1101-5

tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu

司美格鲁肽中央体(侧链)

CAS：1118767-16-0

Commercial

1101-6

Glycine,L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-

L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyChemicalbookl-

L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-

L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-（母环）

司美格鲁肽中央体 (P29)

CAS 1169630-82-3

Commercial

NO.

Product Name

Structure

Status

1201

Sacubitril intermediates 沙库巴曲中央体

1201-1

tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan

-2-yl)carbamate

LCZ696中央体

CAS:1426129-50-1

Commercial

1201-2

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)

amino)-2-methylpent-2-enoic acid

(R,E)-5-([1,1'-联苯]-4-基)-4-[(叔丁氧羰基)氨基]-2

-甲基-2-戊烯酸

CAS:1012341-48-8

Commercial

1201-3

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)

amino)-2-methylpentanoic acid

 (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸

CAS:1012341-50-2

Commercial

1201-4

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

（2R,4S）-4-氨基-5-（联苯-4-基）-2-甲基戊酸乙酯盐酸盐

CAS:149690-12-0

Commercial

1301

Dapagliflozin intermediates 达格列净中央体

1301-1

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-

(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

(2R,3R,4R,5S,6S)-2-(乙酰氧基甲基)-6-(4-氯-3-(4-乙氧基苄基)

苯基)四氢-2H-吡喃-3,4,5-三乙酸酯

CAS:461432-25-7

Commercial

1401

Edoxaban intermediates 艾多沙班中央体

1401-1

tert-butyl ((1R,2S,5S)-2-amino-5-

(dimethylcarbamoyl)cyclohexyl)carbamate

[(1R,2S,5S)-2-氨基-5-[(二甲基氨基)羰...;5S)-2-氨基-5-[(二甲基氨基)羰基]环己基]氨基甲酸叔丁酯

CAS: 365998-36-3

Commercial

1401-2

5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid

艾多沙班中央体

CAS: 720720-96-7

Commercial

NO.

Product Name

Structure

Status

1501

Rimegepant Sulfate intermediates  硫酸瑞美吉泮中央体

1501-1

(5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride

(5S,6S,9R)-6-(2,3-二氟苯基)-9-((三异丙基硅)氧基)-6,7,8,9-四氢-5H-环庚[B]吡啶-5-胺盐酸盐

CAS: 1373116-04-1

Pilot Stage

1501-2

(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol

(5S,6S,9R)-5-氨基-6-(2,3-二氟苯基)-6,7,8,9-四氢-5H-环庚[b]吡啶-9-醇

CAS: 1373116-05-2

Pilot Stage

1501-3

(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol:dihydrochloride

(5S,6S,9R)-5-氨基-6-(2,3-二氟苯基)-6,7,8,9-四氢-5H-环庚[b]吡啶-9-醇二盐酸盐

CAS: 1373116-07-4

Pilot Stage

1501-4

1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one

1-(1-(1H-咪唑酸乙酯-1-羰基)吡啶-4-YL)-1H-咪唑[4,5-B]吡啶-2(3H)-酮

CAS: 1373116-06-3

Pilot Stage

NO.

Product Name

Structure

Status

1601

Olmesartan Medoxomil intermediates 奥美沙坦酯中央体

1601-1

Ethyl4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate

4-(1-羟基-1-甲基乙基)-2-丙基-1H-咪唑-5-羧酸乙酯

CAS: 144689-93-0

Commercial

1601-2

Trityl olmesartan medoxomil

三苯甲基奥美沙坦

CAS：144690-92-6

Commercial